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Most anabolic steroids and other banned substances are no longer detectable in urine within a month or two from last use, and growth hormone is not detected in routine sports panel urine testing, says a new government-funded study on steroids and brain injury published in the Canadian Medical Association Journal.
“A lot of athletes are using steroids, but they’re probably not getting a lot of them back,” says Dr. Paul W. D’Adamo, a family physician and president of the Canadian Society for Sports Neurology.
Dr. D’Adamo, a former National Football League player, co-authored the report with Dr. Robert E. Paus, a UBC researcher who has examined brain disease in football players over a 20-year period.
To determine the true number of steroid users, researchers compared steroid detection rates in the Canadian Institutes of Health Research drug-screening sample with steroid testing in professional teams in Major League Baseball. Among other differences, steroid users in the NHL use performance-enhancing substances like human growth hormone (HGH). The NHL has banned performance-enhancing substance use for more than two decades.
They found that the steroid detection rates among athletes in the study were similar to those seen in professional baseball but were about 10 percent higher than in hockey.
The authors found that among Canadian athletes, 1 percent of people had used steroids within the last year. For high school athletes, that number was 1.1 percent. The highest number of positive urine samples was found among high school athletes (5.5 percent).
The study found that steroid users had significantly higher total testosterone levels than healthy athletes. The testosterone levels were about 1 to 2 times higher in steroid users than in nonusers.
In the previous 20 years of hockey studies, “we don’t know whether there is an association between steroid use and any increased incidence of brain damage in hockey players,” says D’Adamo. “Maybe there is a connection.” But “it’s tough to prove” that in a short-term study, he says. “We’d need a yearlong follow-up study.”
More research will be needed to confirm that. Steroid users had significantly higher levels of IGF-1 in their bloodstreams than did nonusers. IGF-1 is a protein made in the liver that helps to form new brain cells.
“It was a little bit of a surprise, although in some ways we are not too surprised,” says D’Adamo.
They found significantly higher levels of GH in the steroid users and lower levels of IGF-1 in nonusers. The authors suggested that GH increases inflammation and inhibits growth of brain cells.
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